If a Claisen Condensation Reaction Is Run Using Methyl Propanoate

question 40

Multiple Choice

If a Claisen condensation reaction is run using methyl propanoate as the reactant,NaOCH₃ is the ideal base.Why is it important to use NaOCH₃ and not NaOCH₂CH₃?

• A)NaOCH₃ is a stronger base than NaOCH₂CH₃,and this reaction requires a stronger base.
• B)NaOCH₃ is a weaker base than NaOCH₂CH₃,and this reaction requires a weaker base.
• C)Transesterfication can occur when esters react,and this transesterfication would result in a mixture of products.
• D)NaOCH₃ is more soluble than NaOCH₂CH₃ in organic solvents,and this reaction requires a full equivalent of base to proceed.A full equivalent of NaOCH₂CH₃ would not dissolve,so the reaction would not proceed.

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