Rank the following compounds in order of increasing reactivity in nucleophilic acyl substitution reactions,starting with the least reactive compound. 
Definitions:
Factorial ANOVA
A statistical method designed to evaluate the impact of two or more variables acting independently at various levels on an outcome variable.
Interaction Effect
Occurs when the effect of one independent variable on the dependent variable changes depending on the level of another independent variable.
Main Effect
Main Effect is a term in statistical analysis, particularly in ANOVA, that refers to the direct influence of an independent variable on a dependent variable, disregarding interactions with other independent variables.
Therapy
Treatment intended to relieve or heal a disorder, often involving psychological or physical methods.
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