A Client Has Been Diagnosed with a Gram-Negative Bacterial Infection

question 22

Multiple Choice

A client has been diagnosed with a gram-negative bacterial infection and has been prescribed a fluoroquinolone for treatment of this infection.What step of the bacterial DNA replication process is most likely being affected by the use of this medication?

• A)It inhibits the enzyme DNA polymerase necessary for DNA replication.
• B)It binds to the enzyme topoisomerase IV,preventing the new DNA strands from migrating to opposite sides of the cell,thus preventing bacterial cell replication.
• C)It inhibits the relaxation of the supercoil prior to the unwinding process,which terminates replication.
• D)It inhibits the unwinding of the two strands of the supercoil,thus terminating replication.

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