A Client Has Been Started on Diltiazem (Cardizem),a Susbstrate of the Cytochrome

question 1

Multiple Choice

A client has been started on diltiazem (Cardizem) ,a susbstrate of the cytochrome CYP3A4 isoenzyme system.The client also takes phenobarbital,an inducer of the CYP3A4 isoenzyme system,for seizures.What does the nurse recognize about diltiazem?

• A)It will not be able to cross the blood brain barrier (BBB).
• B)It will be metabolized by the kidneys.
• C)It might be inactivated at a faster rate than normal.
• D)It might be excreted at a slower rate.

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Definitions:

Bank Clearing Time

The process and time required for checks and other transactions to be processed through a bank or clearinghouse and the funds to become available.

Processing Time

The time required to complete a particular process, such as manufacturing or data processing.

Weighted Average Delay

The mean delay time, taking into account the importance or weight of each contributing factor to the overall delay.

Cheques

Written, dated, and signed instruments that direct a bank to pay a specific sum of money to the bearer or a specific individual.