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Unlike sweet,salty,sour,or umami,the "bitter" category of tastants includes wide structural variety of detected molecules.Multiple receptors are required to sense the different bitter tastants.What do they have in common? Bitter taste is thought to have evolved as a warning system for toxic compounds.
-The bitter receptor hTAS2R38 is activated by glucosinolates found in plants such as turnips and broccoli.Glucosinolates can block synthesis and transport of iodine.Before the advent of iodized salt,this was a particular problem in areas of the world that are naturally low in iodine.Why might the human population include different variants of the hTAS2R38 gene?
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