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Distinguish Between Driver Mutations and Passenger Mutations in Cancer

question 29

Essay

Distinguish between driver mutations and passenger mutations in cancer. How many driver mutations might be expected in cancers?


Definitions:

Pulmonary Trunk

The major blood vessel that carries blood from the heart's right ventricle to the lungs for oxygenation.

Superior Vena Cava

A large vein that carries deoxygenated blood from the upper half of the body to the heart.

Gap Junctions

Specialized intercellular connections between a multitude of animal cell-types that directly connect the cytoplasms of two cells, allowing various molecules, ions, and electrical impulses to directly pass through a regulated gate between cells.

Cardiac Muscle Cell

Specialized muscle cells found only in the heart, featuring unique properties such as automaticity and the ability to contract as a unit.

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