Concerning Disorders Resulting from Unstable Expansion of Tandem Oligonucleotide Repeats

question 37

Multiple Choice

Concerning disorders resulting from unstable expansion of tandem oligonucleotide repeats, which, if any of the following statements is false.

• A) The expansions can occur in coding DNA in some cases, and in noncoding DNA in other cases.
• B) The repeats are of a variable number of nucleotides (from three to six) in both coding DNA and noncoding DNA.
• C) The expansions in noncoding DNA are generally much larger in size than those in coding DNA.
• D) The expanded arrays in noncoding DNA always result in loss of function of the host gene or of a neighboring gene.

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