Fill in the Blanks Using Numbers

question 28

Essay

Fill in the blanks using numbers.
Depending on our ethnic background, each of us carries about ___1___or so mutations that would be expected to result in loss of gene function (with an average of ___2____ genes that are homozygously inactivated), plus about ____3____ missense variants that severely damage protein structure. When you factor in additional mutations in noncoding DNA, a normal person might be expected to have a total of over ____4____ damaging DNA variants.

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Definitions:

Ductile Behavior

The ability of a material to undergo significant deformation under stress before breaking, often applied to metals and geological formations.

Brittle Deformation

The breaking or fracturing of a rock under stress, without significant deformation.

Crustal Levels

Various layers within the Earth's crust, each having distinct properties and compositions.

Tectonic Forces

The movement and dynamics within the Earth's crust that result in the formation of geological features.