In the Sequence Below, the Blue Sequence Represents an Exon

question 11

Essay

In the sequence below, the blue sequence represents an exon containing coding DNA near the beginning of a large gene and green lines and letters are flanking intron sequence. Nine mutations are shown: an insertion of an Alu repeat insertion plus three deletions at top and five single nucleotide substitutions below. Comment on the mutation class in each case and on its likely effect.

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Definitions:

Research Hypotheses

Proposed explanations or predictions that are based on limited evidence as a starting point for further investigation.

Factorial Analysis

An analytical technique for interpreting the variability in observed, correlated variables through fewer unseen variables termed factors.

Interaction Effects

Occur when the effect of one variable depends on the level of another variable in statistical models.

Independent Variables

Variables that are manipulated or changed in an experiment to test their effects on dependent variables.