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Studies of Single Gene Disorders Have Sought to Draw Correlations

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Studies of single gene disorders have sought to draw correlations between the genotypes at a disease locus and the phenotype of the single gene but the genotype-phenotype correlations are often poor. Even within families there may be significant variability in the phenotype of affected members (who are expected or known to have the same genotypes at the disease locus). List three factors that can explain why that should be so.


Definitions:

Availability

The ease with which a particular piece of information can be recalled from memory, often influenced by how recent or emotionally charged the information is.

Powerful Examples

Highly effective and memorable instances used to illustrate a point or guide behavior.

Misinformation

False or inaccurate information that is spread, intentionally or unintentionally.

Post-Truth

a cultural condition in which objective facts are less influential in shaping public opinion than appeals to emotion and personal belief.

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