With Reference to Aberrant Methylation of Bases Which of the Following

question 25

Multiple Choice

With reference to aberrant methylation of bases which of the following statements, if any, is false?

• A) S-adenosylmethionine donates methyl groups to a range of different molecules in cells and frequently inappropriately methylates bases in DNA.
• B) Guanine is occasionally methylated to give O-6-methylguanine which base pairs with adenine rather than with cytidine.
• C) In each nucleated cell, about 300-600 adenines are converted to 3-methyladenine per day.
• D) 3-methyladenine can be a cytotoxic base: it distorts the double helix and that can disrupt crucial DNA-protein interactions.

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Definitions:

Random Assignment

A method used in experiments to assign participants to different groups in a way that each participant has an equal chance of being in any group, thereby helping to reduce bias.

Extreme Cases

Situations or examples that are unusual or rare, often used to illustrate the outer limits of possible outcomes or behaviors.

Random Sampling Procedure

A method of selecting a sample from a population in which each member has an equal probability of being chosen.

Equal Chance

The concept that every participant or element in a given situation has the same probability of being selected or occurring.