To Treat Some of the Symptoms of Myasthenia Gravis,physicians Sometimes

question 85

Multiple Choice

To treat some of the symptoms of Myasthenia gravis,physicians sometimes prescribe the anticholinesterase drug neostigmine.Why does this drug help with the symptoms of muscle weakness and fatigue?

• A)The drug inhibits the production of the antibodies which the patient's immune system forms against ACh receptors.It thereby prevents the breakdown of ACh receptors so the muscle cells receive the normal contraction stimuli.
• B)The drug increases the amount of acetylcholine released by the neuron,thereby increasing the chance that the few ACh remaining receptors on the muscle fiber membranes will bind ACh and receive the signal to contract.
• C)The drug inhibits the activity of acetylcholinesterase,which prevents the breakdown of ACh.Consequently,ACh levels in the synapse remain elevated,thereby increasing the stimulation of the reduced number of functional ACh receptors.
• D)The drug acts as an AP and signals the release of ACh.Consequently,ACh levels in the synapse remain elevated,thereby increasing the stimulation of the reduced number of functional ACh receptors.
• E)The drug increases the activity of acetylcholinesterase.ACh is then broken down more quickly,thereby allowing a quicker signal cycle.

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