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Use the following information when answering the corresponding questions) .
It has been shown that there are two distinct variants of the HIV virus Bleul et al. 1997. The HIV coreceptors CXCR4 and CCR differentially regulated on human T- lymphocytes. Proceedings of the National Academy of Science 94:1925- 30) . One virus preferentially infects macrophages and is called M- tropic. The other preferentially infects T cells and is called T- tropic. The M- tropic viruses use CCR5 and CD4 as coreceptors, and the T- tropic viruses use CXCR4 and CD4 as coreceptors. The
M- tropic viruses are found early in HIV infections; the T- tropic viruses are found late in infections, when AIDS symptoms are prevalent. T- tropic viruses are associated with a drastic decrease in T cells. Macrophages go to the site of wounds, where they are used to fight infections. T cells circulate in the body and fight infections at many sites.
-Which receptors for HIV would you expect to find on macrophages and T cells?
Educational Achievement
The accomplishment of educational milestones or the attainment of knowledge or skills, often measured through grades, diplomas, or standardized test scores.
Intelligence
The capacity to learn, understand, and apply knowledge, solve problems, and adapt to new situations.
Gray Matter
Brain tissue that contains nerve cell bodies and is involved in muscle control and sensory perception.
White Matter
A component of the brain and spinal cord made up of myelinated axons, which facilitates communication between different brain regions.
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