How Might a Single Base Substitution in the Sequence of a Gene

question 21

Multiple Choice

How might a single base substitution in the sequence of a gene affect the amino acid sequence of a protein encoded by the gene, and why?

• A) The amino acid sequence would be substantially altered, because the reading frame would change with a single base substitution.
• B) It is not possible for a single base substitution to affect protein structure, because each codon is three bases long.
• C) Only a single amino acid could change, because the reading frame is unaffected.
• D) All amino acids following the substitution would be affected, because the reading frame would be shifted.

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Definitions:

Useful Life

The estimated duration of time an asset is expected to remain functional and economically feasible for its intended use.

Straight-Line Depreciation

A strategy for spreading out the expenditure of a physical asset over the duration of its useful life in uniform annual payments.

Residual Value

The estimated value that an asset will realize upon its sale at the end of its useful life, important in calculating depreciation.

Sales Tax

A sales tax is a government-imposed levy on the sale of goods and services, which is usually a percentage of the retail price.