In 1985, Hassold and Chiu Found That the Likelihood of Miscarriage

question 12

Multiple Choice

In 1985, Hassold and Chiu found that the likelihood of miscarriage increased with maternal age. What is the most likely explanation for the relationship between age and miscarriage?

• A) Older women typically have hormonal imbalances that prevent them from carrying a baby to term.
• B) Women in their mid- thirties and older have more health problems that interfere with their ability to maintain pregnancy.
• C) Ova are arrested in meiosis until ovulation. As a result, completion of meiosis in the older woman is more likely to result in aneuploidy or other chromosomal abnormalities.
• D) The DNA replication that takes place immediately prior to meiosis is less accurate in older women.

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