A Knockout Mutation in the X-Inactive Specific Transcript (XIST)lncRNA of Mice

question 8

Multiple Choice

A knockout mutation in the X-inactive specific transcript (XIST) lncRNA of mice would result in

• A) one inactivated X chromosome in female mice.
• B) the inhibited transcription and translation of X-linked proteins.
• C) two inactive X chromosomes in female mice.
• D) two active X chromosomes in female mice.

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Definitions:

Place Theory

A theory explaining how sound frequency is encoded in the cochlea of the inner ear, suggesting that specific places along the basilar membrane respond to specific frequencies.

High-Frequency

Relating to or denoting a band of the electromagnetic spectrum or sound above the range of normal human hearing.

Intermediate-Frequency

Refers to the frequency that lies between the radio frequency (RF) and the audio frequency (AF) bands, commonly used in communication electronics for signal processing.

Volley Principle

A theory in neuroscience that suggests multiple neurons can collectively transmit a higher frequency of signals by firing in synchronization, especially relevant in the context of auditory processing.