Glutamine-PRPP Amidotransferase Is a Tetrameric Enzyme That Displays Sigmoidal Kinetics

question 10

Short Answer

Glutamine-PRPP amidotransferase is a tetrameric enzyme that displays sigmoidal kinetics when no inhibitors are present.In the presence of either GTP or ATP the kinetics curve is sigmoidal.Why does this difference in kinetics occur?

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Definitions:

Jomon

Japanese, “cord markings.” A type of Japanese ceramic technique characterized by ropelike markings.

Ise Shrine

is a Shinto shrine dedicated to the goddess Amaterasu-ōmikami, located in Ise, Japan, notable for its tradition of being rebuilt every 20 years.

Kondo

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A central figure in Japanese Buddhist iconography, Yakushi Nyorai, flanked by two attendants, symbolizing healing and medicine.