How Would Individuals with Decreased Levels of the Pentose Phosphate

question 50

Multiple Choice

How would individuals with decreased levels of the pentose phosphate enzyme glucose-6-phosphate dehydrogenase respond to oxidative stress?

• A) Higher than normal levels of NADPH would accumulate.
• B) They would not have the ability to regenerate reduced glutathione as rapidly.
• C) They would rapidly neutralize cellular levels of H₂O₂ and other reactive oxygen species.
• D) They would compensate with higher than normal levels of pentose phosphate pathway activity.

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Definitions:

NMR Spectroscopy

A spectroscopic method that utilizes the magnetic characteristics of specific atomic nuclei to identify the physical and chemical properties of atoms or the molecules they are part of.

Cyclohexane

A saturated hydrocarbon with the formula C6H12, featuring a ring structure of six carbon atoms.

Axial

"Axial" refers to positions or orientations along the axis of a molecule, usually in cyclic compounds, opposed to equatorial positions which are off the axis.

Equatorial

Referring to the position of substituents in a cyclohexane ring, where they are oriented parallel to the equator of the molecule, leading to less steric strain.