Classify the reaction that occurs at step 4 in the reaction schematic of the pyruvate dehydrogenase reaction below. 
Definitions:
Metabolism
The complex of life-sustaining chemical transformations within the cells of living organisms.
Lazarus
A psychologist who developed the theory of stress and coping, which examines how individuals respond to psychological stress.
Interpretation
The process of explaining the meaning of something, often in a particular context or perspective.
Stress
A state of mental or emotional strain resulting from adverse or demanding circumstances.
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