A Mutation in The $\beta$ Subunit of Hemoglobin Is Discovered That Reduces the Affinity of That

question 79

Multiple Choice

A mutation in the $\beta$ subunit of hemoglobin is discovered that reduces the affinity of 2,3-BPG binding. Which of the following mutations is most likely to have this consequence?

• A) Val1 \(\rightarrow\) Ile1
• B) Asp99 \(\rightarrow\) Glu99
• C) Lys82 \(\rightarrow\) Asp82
• D) Glu6 \(\rightarrow\) Val6

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