Decide if the rate of malate transport by the Omp32 protein of Delftia acidovorans will be affected if the pH of the system is changed from 6.8 to 8.2. Explain your reasoning.
The pKa of amino acids with ionizable side chains are provided in the table below. Note that malic acid contains two ionizable groups with pKa of 3.40 and 5.20. Assume in this scenario that the pH change does not alter the overall conformation of the protein.
Definitions:
Therapeutic Effect
The beneficial outcomes or purposes of a treatment or medication in improving a patient's condition or symptoms.
Bowel Movement
Refers to the process of excreting waste from the large intestine through the rectum and anus, essential for digestive health.
Left Sims's Position
A patient positioning method for rectal and vaginal examinations, enemas, and childbirth where the individual lies on their left side with the right knee bent and drawn up toward the chest.
Administer Enema
The process of introducing a fluid into the rectum and colon via the anus to stimulate bowel movement or for diagnostic purposes.
Q6: Which class of proteins interacts with a
Q8: Which linear sequence of bonded atoms can
Q12: Vitamin C is required for prolyl hydroxylase
Q18: Is the net reaction favorable for
Q27: When DNA is transcribed into RNA, the
Q37: What are the three major types of
Q51: You design an experiment in which
Q80: Polyclonal antibodies are<br>A) derived from B cells
Q93: Which of the following does NOT participate
Q97: Which of the following pathways are found