You Are Studying a Biochemical Pathway That Requires ATP as an Energy

question 22

Multiple Choice

You are studying a biochemical pathway that requires ATP as an energy source.To your dismay, the reactions soon stop, partly because the ATP is rapidly used up and partly because an excess of ADP builds up and inhibits the enzymes involved.You are about to give up when the following table from a biochemistry textbook catches your eye. $\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\text {hydrolysis}$
$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\underline{\text {reaction}}$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$$\quad$ $\Delta G^{\circ}$
$\text { creatine + ATP } \quad\quad\quad\quad \stackrel{\text { enzyme A }}{\longrightarrow} \text { creatine phosphate + ADP +3 kcal/mole }$

$\text { ATP }+\mathrm{H}_{2} \mathrm{O} \quad\quad\quad\quad\quad \stackrel{\text { enzyme B }}{\longrightarrow} \mathrm{ADP}+\text { phosphate } \quad \quad\quad\quad-7.3 \mathrm{kcal} / \text { mole }$

$\text { pyrophosphate }+\mathrm{H}_{2} \mathrm{O} \quad \stackrel{\text { enzyme } \mathrm{C}}{\longrightarrow} 2 \text { phosphate } \quad\quad\quad\quad \quad\quad\quad\quad-7 \mathrm{kcal} / \text { mole }$

glucose 6-phosphate $+\mathrm{H}_{2} \mathrm{O} \quad\stackrel{\text { enzyme D }}{\longrightarrow}$ qlucose + phosphate $\quad\quad\quad\quad\quad\quad\quad-3.3 \mathrm{kcal} / \mathrm{mole}$
Table 3-43
Which of the following reagents is/are most likely to revitalize your reaction?

• A)a vast excess of ATP
• B)glucose 6-phosphate and enzyme D
• C)creatine phosphate and enzyme A
• D)pyrophosphate

---

Definitions:

Jumping Rope

A form of cardiovascular exercise that involves skipping over a rope that is swung under the feet and over the head, beneficial for coordination and stamina.

Cardiovascular Disease

A class of diseases that involve the heart or blood vessels, including coronary artery disease, hypertension, and stroke.

Stroke

A medical condition characterized by the sudden loss of blood circulation to an area of the brain, resulting in loss of neural function.

High-Impact Exercise

Physical activities that involve vigorous movement and can exert a lot of stress on the bones and joints, often involving both feet leaving the ground at the same time.