The Sliding Clamp Complex Must Be Reloaded for the Synthesis

question 30

Essay

The sliding clamp complex must be reloaded for the synthesis of each Okazaki fragment on the lagging strand, while on the leading strand the clamp complex remains assembled over much longer stretches of DNA.Considering this information, explain how the cell is able to replicate the leading and lagging strands at the same rate.

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Definitions:

Heart Failure

A chronic condition where the heart is unable to pump blood effectively, leading to accumulated fluids and shortness of breath.

Pulmonary Congestion

Accumulation of fluid in the lungs, often leading to difficulty breathing and other respiratory symptoms.

Tetralogy of Fallot

A congenital heart defect that involves four anatomical abnormalities of the heart.

Ventricular Septal Defect

A congenital heart defect characterized by an opening in the septum separating the heart's two lower chambers, allowing blood to pass from the left to the right ventricle.