In a Method Called Patch-Clamping, a Glass Capillary Can Be

question 8

Multiple Choice

In a method called patch-clamping, a glass capillary can be converted into a microelectrode that measures the electrical currents across biological membranes.Which of the following statements about the patch-clamp method is FALSE?

• A)The glass capillary adheres to a "patch" of membrane through the application of suction.
• B)The aperture in the glass capillary used to make a microelectrode is about 1 μm in diameter.
• C)If the experimental conditions are held constant, fluctuations in electrical currents across the patch of membrane are still observed.
• D)Single-channel patch-clamp recordings have demonstrated that gated membrane channels will only open and close in response to specific stimuli.

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