Using Genetic Engineering Techniques, You Have Created a Set of Proteins

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The Answer is A.The protein would enter the ER.The signal for a protein to enter the ER is recognized as the protein is being synthesized and the protein will end up either in the ER or on the ER membrane.Cytosolic nuclear transport proteins recognize proteins destined for the nucleus once those proteins are fully synthesized and fully folded.
B.The protein would enter the mitochondria.For a nuclear export signal to work, the protein would have to end up in the nucleus first and thus would need a nuclear import signal for the nuclear export signal to be used.
C.The protein would enter the mitochondria.To be retained in the ER, the protein needs to enter the ER.Because there is no signal for ER import, the ER retention signal would not function.

Using Genetic Engineering Techniques, You Have Created a Set of Proteins

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