Cell Lines a and B Both Survive in Tissue Culture

question 50

Multiple Choice

Cell lines A and B both survive in tissue culture containing serum but do not proliferate.Factor F is known to stimulate proliferation in cell line A.Cell line A produces a receptor protein (R) that cell line B does not produce.To test the role of receptor R, you introduce this receptor protein into cell line B, using recombinant DNA techniques.You then test all of your various cell lines in the presence of serum for their response to factor F, with the results summarized in Table 16-9. $\begin{array} { l l l } \text { Cell line } & \text { Factor } F & \text { Response } \\\hline \text { A } & \text { - Factor F } & \text { Cells do not proliferate } \\\text { A } & \text { + Factor F } & \text { Cells proliferate } \\\text { B } & \text { - Factor F } & \text { Cells do not proliferate } \\\text { B } & \text { + Factor F } & \text { Cells do not proliferate } \\\text { B + receptor R } & \text { - Factor } F & \text { Cells proliferate } \\\text { B + receptor R } & \text { + Factor F } & \text { Cells proliferate }\end{array}$ Table 16-9
Which of the following cannot be concluded from your results above?

• A)Binding of factor F to its receptor is required for proliferation of cell line A.
• B)Receptor R binds to factor F to induce cell proliferation in cell line A.
• C)Cell line A expresses a receptor for factor F.
• D)Factor F is not required for proliferation in cell line B.

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Definitions:

LIFO

A method to value inventory that assumes the latest items added to inventory are the first ones used or sold.

Perpetual Inventory

An accounting method where inventory quantities and costs are updated in real-time with each sale or purchase.

Ending Inventory

The total value of all products, goods, and materials in stock at the end of an accounting period.

Interim Financial Statements

Financial reports covering a period of less than a full fiscal year, often quarterly.