Intermediate Filaments Are Made from Elongated Fibrous Proteins That Are

question 49

Multiple Choice

Intermediate filaments are made from elongated fibrous proteins that are assembled into a ropelike structure.Figure 17-6 shows the structure of an intermediate filament subunit.You are interested in how intermediate filaments are formed, and you create an intermediate filament subunit whose α-helical region is twice as long as that of a normal intermediate filament by duplicating the normal α-helical region while keeping a globular head at the N-terminus and a globular tail at the C-terminus; you call this subunit IFαd.If you were to assemble intermediate filaments using IFαd as the subunit, which of the following predictions describes the most likely outcome? Figure 17-6

• A)Filaments assembled using IFαd will interact with different cytoskeletal components.
• B)Filaments assembled using IFαd will form dimers that are twice as long as dimers assembled from normal intermediate filaments.
• C)Sixteen tetramers assembled from IFαd will be needed for a ropelike structure to form.
• D)Dimers of IFαd will form by interactions with the N-terminal globular head and the C-terminal globular tail.

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