You Create Cells with a Version of the Origin Recognition

question 42

Multiple Choice

You create cells with a version of the origin recognition complex, ORC, that cannot be phosphorylated by S-Cdk and thus cannot be inactivated.Which of the following statements describes the likely consequence of this change in ORC?

• A)Cells will enter S phase prematurely.
• B)Cells will replicate some regions of the genome more than once in a cell cycle.
• C)ORC will be unable to bind to DNA.
• D)DNA helicases will not be able to open up the double helix at the replication origin.

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Definitions:

Small Intestine

A part of the digestive system where most of the digestion and absorption of nutrients takes place, extending from the stomach to the large intestine.

Secretin

A hormone produced by the small intestine that stimulates the pancreas to release bicarbonate-rich fluid, aiding digestion.

Pancreatic Duct

A conduit through which digestive enzymes from the pancreas are transported to the small intestine.

Pancreatic Acinar Cells

The cells in the pancreas that produce digestive enzymes, which are secreted into the small intestine.