APC Is a Tumor Suppressor and Acts in the Wnt

question 38

Multiple Choice

APC is a tumor suppressor and acts in the Wnt signaling pathway to prevent the TCF complex from turning on Wnt-responsive genes.Mice that lack the gene encoding TCF4 do not have the ability to maintain the pool of proliferating gut stem cells needed to renew the gut lining.What do you predict will happen in mice that lack the APC gene?

• A)Like the mice lacking TCF4, they will not be able to renew the gut lining.
• B)They will have inappropriate proliferation of gut stem cells.
• C)Mice lacking the APC gene will have a hyperactive Wnt receptor even though there is no Wnt signal.
• D)Mice lacking the APC gene will be like normal healthy mice, since APC is a tumor suppressor and thus not needed unless there is a tumor present.

---

Definitions:

Repetitive Strain Injuries

Physical ailments caused by repeated motion or overuse, affecting muscles, nerves, and tendons, common in workplace environments.

Self-leadership

A process where individuals influence themselves to achieve the self-direction and self-motivation necessary to perform.

Empowerment Increases

Empowerment Increases refer to the enhancement of individuals' or groups' ability to make choices, take effective actions, and influence outcomes within their roles or communities.

Autonomy

The degree of freedom an individual or entity has to make decisions independently, without external control.