A Nurse Is Reviewing Drug Safety with a Student Nurse

question 10

Multiple Choice

A nurse is reviewing drug safety with a student nurse. The nurse explains that the median lethal dose of drugs is often determined in laboratory preclinical trials because of which factors? Note: Credit will be given only if all correct choices and no incorrect choices are selected. Select all that apply.

• A) It would be unethical to determine these values in human subjects.
• B) The safety of the medication must be determined prior to clinical trials.
• C) It is difficult to obtain sufficient participants for clinical trials.
• D) Clinical trials determine only the effective dose of a drug.
• E) It is too costly to conduct the studies during clinical trials.

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Definitions:

Break-Even Point

The financial analysis term where total costs and total revenues are equal, resulting in no net loss or gain for the business.

Contribution Margin

Contribution margin is the amount remaining from sales revenue after variable expenses are deducted, showing how much contributes to covering fixed costs and profit.

Fixed Costs

Costs that remain constant regardless of a company's operational levels, including rent, wages, and insurance fees.

Absorption Costing

An approach for assigning costs to a product that integrates all aspects of manufacturing expenses, from direct materials and labor to both types of overheads - fixed and variable.