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Your Niece Has Been Diagnosed with Diamond-Blackfan Anemia, an Extremely

question 26

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Your niece has been diagnosed with Diamond-Blackfan anemia, an extremely rare disorder of the bone marrow that causes people have a low red blood cell (RBC) count. The disease is classified as a ribosomal protein disease, meaning that one or more of the genes involved in ribosome production is/are mutated, and the ribosomes are not synthesized properly. Although it is not currently understood why mutations in ribosome biosynthesis affect blood cell formation particularly, you are able to help your sister understand the role of ribosomes in the cell and the consequence of ribosome failure, so that she has a better grasp of her child's condition.
-You explain to your sister that ribosomes are the site of ________ in cells.


Definitions:

Self-Motivated

The quality of being driven to do or achieve something because of one's own enthusiasm or interest, without needing pressure from others.

McClelland's Model

A theory of motivation that emphasizes three primary needs influencing human motivation: the need for achievement, the need for affiliation, and the need for power.

Hygiene Factors

Elements of a job that do not increase job satisfaction but, when absent, can lead to dissatisfaction, according to Herzberg's two-factor theory.

Herzberg's Model

A theory of motivation proposing that certain factors cause job satisfaction, while a separate set of factors cause dissatisfaction.

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