Your Niece Has Been Diagnosed with Diamond-Blackfan Anemia, an Extremely

question 26

Multiple Choice

Your niece has been diagnosed with Diamond-Blackfan anemia, an extremely rare disorder of the bone marrow that causes people have a low red blood cell (RBC) count. The disease is classified as a ribosomal protein disease, meaning that one or more of the genes involved in ribosome production is/are mutated, and the ribosomes are not synthesized properly. Although it is not currently understood why mutations in ribosome biosynthesis affect blood cell formation particularly, you are able to help your sister understand the role of ribosomes in the cell and the consequence of ribosome failure, so that she has a better grasp of her child's condition.
-You explain to your sister that ribosomes are the site of ________ in cells.

• A) protein synthesis
• B) lipid synthesis
• C) peptidoglycan synthesis
• D) DNA replication
• E) the nucleolus

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Definitions:

Functional

Designed to be practical and useful, often relating to the specific duties or activities that an object or person performs.

Geographical Departmentalization

An organizational structure in which departments are organized based on geographic regions or areas.