Why Is the Hemoglobin S Allele Found in Very High

question 58

Essay

Why is the hemoglobin S allele found in very high frequencies in some populations even though it is a lethal recessive?

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Definitions:

Epoxypentan-1-ol

An organic compound featuring a five-carbon chain with an epoxide ring (a three-membered ring consisting of an oxygen atom and two carbon atoms) and a hydroxyl group at the first carbon.

Hydroxyethyl

A functional group or moiety featuring an ethyl backbone attached to a hydroxyl group, often represented as -CH2CH2OH.

Oxirane

Another term for ethylene oxide, a three-membered cyclic ether (epoxide) with the formula C2H4O, used as an important industrial chemical and intermediate.

Bond Angle

The angle formed between two bonds at the atom where they meet, influencing the molecule's geometry.