An Important Reaction in the Production of Energy from Sugars

question 23

Multiple Choice

An important reaction in the production of energy from sugars (glycolysis) is the reduction of pyruvate to lactate by NADH. pyruvate + NADH + H⁺(aq) → lactate + NAD⁺ Δ_rG°′ = ?
Given the following reduction potentials,
NAD⁺ + H⁺ + 2e− → NADH
Ε°′ = −0.320 V
Pyruvate + 2H⁺ + 2e⁻ → lactate
Ε°′ = −0.190 V
Calculate the standard Gibbs free energy (at pH 7) for the reduction of pyruvate to lactate by NADH.(Δ_rG°′ = −nFE°′; F = 96485 C/mol electrons)

• A) 98.4 kJ/mol-rxn
• B) −98.4 kJ/mol-rxn
• C) −12.6 kJ/mol-rxn
• D) 25.1 kJ/mol-rxn
• E) −25.1 kJ/mol-rxn

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