Ordered: Granisetron Hydrochloride Injection (Kytril) $10 \text { mcg per kg }$

question 13

Essay

Ordered: Granisetron hydrochloride injection (Kytril) $10 \text { mcg per kg }$ IV injection $30 \mathrm{~min}$ before chemotherapy to reduce nausea and vomiting.
Available: Kytril vial IV $0.1 \mathrm{mg} \text { per } \mathrm{mL}$ Patient weight: $60 \mathrm{~kg}$ .
Dilution: May be given undiluted as an injection into a port over $30 \text { seconds. }$ The nurse adds $2.4 \mathrm{~mL}$ of sterile NS for injection to the medication for ease of timing the injection rate into the injection port.
a. What is the total dose of drug in mg to be given?
b. What is the total volume of drug for injection?
c. How many total seconds per calibration?

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Definitions:

Parabolic Shape

The shape of the graph of a quadratic function, resembling a curve that opens upwards or downwards.

Linearity

The attribute of a relationship or function that can be graphically represented as a straight line, indicating a constant rate of change.

P-Value

The probability of obtaining test results at least as extreme as the results actually observed, under the assumption that the null hypothesis is correct.

Slope Coefficient

A measure in statistics that represents the rate of change in the dependent variable per unit change in an independent variable in a linear model.