Ordered: Granisetron Hydrochloride Injection (Kytril) $10 \text { mcg per kg }$

question 13

Essay

Ordered: Granisetron hydrochloride injection (Kytril) $10 \text { mcg per kg }$ IV injection $30 \mathrm{~min}$ before chemotherapy to reduce nausea and vomiting.
Available: Kytril vial IV $0.1 \mathrm{mg} \text { per } \mathrm{mL}$ Patient weight: $60 \mathrm{~kg}$ .
Dilution: May be given undiluted as an injection into a port over $30 \text { seconds. }$ The nurse adds $2.4 \mathrm{~mL}$ of sterile NS for injection to the medication for ease of timing the injection rate into the injection port.
a. What is the total dose of drug in mg to be given?
b. What is the total volume of drug for injection?
c. How many total seconds per calibration?

---

Definitions:

Carbon Dioxide

A colorless, odorless gas produced by burning carbon and organic compounds and by respiration, exhaled as a waste product.

Ketone Bodies

Metabolic byproducts produced from the breakdown of fatty acids, used as an energy source when glucose is scarce.

Diabetes Mellitus

Metabolic disease in which carbohydrate use is reduced and that of lipid and protein enhanced; caused by a deficiency of insulin or an inability to respond to insulin and is characterized, in more severe cases, by hyperglycemia, glycosuria, water and electrolyte loss, ketoacidosis, and coma.

Proton Pump

An integral membrane protein that builds up a proton gradient across a biological membrane by actively transporting protons.