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A 26-year-old day laborer with a long history of anemia has a several months' history of dyspnea, fever, and pulmonary pain.Additionally, he complains of tightness in the chest and upper abdominal region.His hematology values are as follows: WBC 15.9 109/L
RBC 2.9 1012/L
Hgb 9.5 g/dL
Hct 30%
MCV 103 fL
MCH 31 pg
MCHC 32%
NRBC 15/100 WBC
Platelets 275 109/L
Reticulocytes 16.8%
The hemoglobin electrophoresis results are as follows:
Hgb A =3%
Hgb A2 = 2%
Hgb S = 85%
Hgb F = 10%
The most likely diagnosis is:
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