What would the restricted regression be if you are interested in testing the null hypothesis and against the alternative hypothesis or for a regression ,? 
Definitions:
Trough Level
The lowest concentration of a drug in the bloodstream, measured just before the next dose is due.
Oxycodone
A potent opioid pain medication used to treat moderate to severe pain, subject to prescription control due to its addictive potential.
Narcotic
A narcotic is a drug affecting mood or behavior and is used for pain relief but can lead to dependence.
Medication Adjustment
The process of changing the type, dosage, or frequency of medications based on a patient's health status.
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