Reoviruses Have Been Used to Study Viral Pathogenesis in Mice

question 4

Multiple Choice

Reoviruses have been used to study viral pathogenesis in mice.Using virus reassortants, which of the following has been shown to be a major determinant for infection of the nervous system in a mouse?

• A) Activation of the host cell immune system.
• B) Binding of the virus to different host cell receptors.
• C) Activation of the interferon system in host cells.
• D) The rate of viral mRNA synthesis in host cells.
• E) The rate of genome synthesis in host cells.