A reaction occurs between the large black spheres and the small grey spheres.Each of the boxes below represents different reaction conditions for that reaction.Which box contains the reaction conditions that leads to the fastest reaction? 
Definitions:
Marijuana
A psychoactive drug from the Cannabis plant used for medical or recreational purposes.
Methadone
A synthetic opioid used for pain management and as part of drug addiction detox programs, particularly for heroin.
Placenta
A structure that forms in the uterus while pregnant, supplying the fetus with oxygen and nutrients while also eliminating waste via the umbilical cord.
Heroin
An opioid drug made from morphine, a natural substance taken from the seed pod of various opium poppy plants, highly addictive and illegal.
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