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As the Most Junior Member of a Lab,you Are Tasked

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As the most junior member of a lab,you are tasked with generating cell lines that accumulate DNA damage to investigate how random mutations affect transformation of cells into cancer cells.You decide to mutate proteins in the p53 pathway.Which three proteins would you mutate? Explain your reasoning.


Definitions:

Reaction Rate

The speed at which a chemical reaction occurs, typically expressed in terms of the concentration of reactants consumed or products formed over time.

Surface Area

The total area that the surface of an object occupies, impacting its chemical reactivity and physical interactions.

Kinetic Energy

The energy possessed by an object due to its motion, calculated as one half the mass times the velocity squared.

Reaction Sites

Specific regions on a molecule where a chemical reaction occurs or is facilitated.

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