Each of the Following Provides Evidence That Kinetochore Microtubule Shortening

question 46

Multiple Choice

Each of the following provides evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole except

• A)Stabilization of microtubules with the drug paclitaxel stops chromosome movement to a pole.
• B)Treatment that accelerates microtubule depolymerization causes chromosomes to move toward the poles more quickly.
• C)Antibody inhibition of kinesin depolymerization of kinetochore microtubules interferes with chromosome movement to a pole.
• D)Laser bleaching of labeled kinetochore microtubules indicates they shorten at the kinetochore as the chromosome moves toward a pole.
• E)All of the above are evidence that kinetochore microtubule shortening is directly involved in anaphase A chromosome movement to a pole.

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