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You Have Determined the Base Sequence for a Gene from Felis

question 40

Essay

You have determined the base sequence for a gene from Felis catus (domestic cat)that you believe may be involved in feline leukemia.A BLASTn search results in nucleotide sequence matches from viruses,not mammals,although the similarity is low.What other bioinformatic tools or techniques could you use to investigate the function of this gene? Why would these tools or techniques be more convincing than a BLASTn search? Hypothesize why you think this result might be correct or incorrect.


Definitions:

Two-tailed Test

A statistical hypothesis test in which the area of interest is in both tails of the probability distribution, considering both directions of an effect.

Level Of Significance

The threshold used to determine the statistical significance of an observed effect; denoted by alpha, typically set at 0.05 or 5%.

P-value

The chance of obtaining test outcomes that are as drastic as, or more drastic than, the ones actually observed, under the premise that the null hypothesis is right.

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