Some Researchers Have Hypothesized That Type II Diabetes Mellitus Is

question 4

Multiple Choice

Some researchers have hypothesized that type II diabetes mellitus is caused by a mitochondrial defect.Which of the following would be the best way for them to study mitochondrial differences in fresh tissue samples from diabetic and nondiabetic mice?

• A)Mitochondria could be identified and isolated from other cellular components using immunofluorescence microscopy in both tissues.
• B)Mitochondria are the only organelles that survive tissue homogenization,thus both tissues could be homogenized to study the mitochondria.
• C)Mitochondria from both tissues could be isolated from other cellular components by using proteolytic enzymes to break down other cellular structures.
• D)Mitochondria from both tissues could be isolated from other cellular components by fractionating tissue homogenate using differential centrifugation followed by density gradient centrifugation.
• E)Mitochondria can not be separated from whole cells without damaging them.

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A standardized, primary screening and assessment tool of health status that forms the foundation of the comprehensive assessment for all residents in long-term care facilities.

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