Researchers Used the CRISPR System to Make 455 Different Cuts

question 51

Multiple Choice

Researchers used the CRISPR system to make 455 different cuts in the porcine endogenous retrovirus (PERV) pol genes in the pig genome.All of the PERV genes were inactivated in the pig embryos even though only 20 percent of the resulting mutations were larger than nine base pairs.The resulting mutations were successful at knocking out the PERV genes because

• A) even single point mutations can be enough to make a gene product useless or inactivate a gene.
• B) large mutations are not useful in knocking out genes.
• C) inactivating 20 percent of the PERV genes is just as good as inactivating 100 percent of the PERV genes.
• D) only 20 percent of the PERV genes need to be inactivated to result in all of them being inactive.

---

Definitions:

Peak-period

A time of maximum activity or demand, often leading to higher prices and increased revenue for companies able to meet the demand.

Logistics Department

The division of a company responsible for the management of the movement and storage of materials, goods, and information.

Operating Divisions

Sections of a business organization that operate semi-autonomously, typically responsible for their own budgeting and profit and loss.

Variable Costs

Expenses that change in proportion to the level of production or sales volume.