What Is One Reason Why Tumor-Suppressor Genes Make Poor Druggable

question 9

Multiple Choice

What is one reason why tumor-suppressor genes make poor druggable targets?

• A)Cancer-causing mutations in tumor-suppressor genes result in loss of function.
• B)Mutant alleles of tumor-suppressor genes generally result in a greater activity of the protein, which makes inhibiting the proteins more difficult.
• C)Most drugs cannot distinguish the normal and mutant forms of the tumor suppressor proteins.
• D)Drugs that can target-tumor suppressor proteins are difficult to deliver to cancer cells.

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