Identifying Candidates for a Disease Gene by Positional Cloning Depends

question 12

Multiple Choice

Identifying candidates for a disease gene by positional cloning depends on distinguishing DNA markers that are close to the disease gene from markers that are far away.When the disease gene is close to a marker, there will be

• A)a high number of mutations in the intervening DNA.
• B)a low rate of recombination between the disease gene and the marker.
• C)many alleles at the marker locus.
• D)a high chance of locus heterogeneity.

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