Many Cancers Have a Mutation That Changes a Valine to a Glutamic

question 21

Multiple Choice

Many cancers have a mutation that changes a valine to a glutamic acid in the RAF kinase protein which phosphorylates proteins that promote cell division.This mutant protein is a constitutively active kinase.What type of allele is this mutant allele?

• A)hypomorphic allele
• B)hypermorphic allele
• C)null allele
• D)antimorphic allele

---

Definitions:

CAPM

The Capital Asset Pricing Model, which describes the relationship between systematic risk and expected return for assets, particularly stocks, suggesting that investors need to be compensated in two ways: time value of money and risk.

Fama and French

Scholars who developed a three-factor model for explaining the risk and return of stocks and other investments.

Econometrics

The application of statistical and mathematical theories to economics for the purpose of testing hypotheses and forecasting future trends.

Asset Betas

Measure the sensitivity of an asset's returns to market returns, representing the systematic risk of assets not attributable to market-wide movements.