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A Large Deletion Removes the Promoter and First Three Exons

question 23

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A large deletion removes the promoter and first three exons of a gene.No mRNA or protein is detected.What type of allele is this mutant allele?


Definitions:

RNA Synthesis

The process by which ribonucleic acid (RNA) molecules are created from DNA templates in cells, essential for gene expression and regulation.

Enhancers

Genetic elements that increase the transcription of specific genes, playing a key role in regulating gene expression.

DNA Sequences

The precise order of nucleotides (adenine, thymine, cytosine, and guanine) within a portion of a DNA molecule, determining genetic information.

Promoters

DNA sequences located upstream of a gene that initiate transcription by binding RNA polymerase and other necessary transcription factors.

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