If a Chemical Inhibitor of DNA Ligase Was Added to Bacterial

question 56

Multiple Choice

If a chemical inhibitor of DNA ligase was added to bacterial cells after DNA replication initiation, the outcome would be

• A)elongation of both strands would not occur without ligase to join new nucleotides together.
• B)elongation would occur, but Okazaki fragments would not be joined together.
• C)elongation of the lagging strand, but not the leading strand would occur.
• D)normal replication would proceed as DNA ligase is not required for this process.
• E)too many supercoils would build up in the DNA, resulting in a halting of elongation.

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