In Rats, the P Gene Allele for Pigmentation (P) Is

question 13

Multiple Choice

In rats, the P gene allele for pigmentation (P) is dominant to the allele for albinism (p) . The B gene allele for black pigmentation (B) is dominant to the allele for cream pigmentation (b) . The pp homozygous recessive genotype is epistatic to any allele combination at gene B.
-Predict the genotypes and phenotypes of the F₁ progeny of a cross between a pure-breeding black rat and an albino that is also homozygous for cream.

• A)PP BB, black
• B)Pp Bb, black
• C)Pp Bb, albino
• D)pp Bb, albino

---

Definitions:

Prion

From proteinaceous and infectious; an abnormally folded protein that causes progressive neurocognitive disorders.

Neurodegenerative Diseases

A group of disorders characterized by the progressive degeneration of the structure and function of the nervous system, affecting mostly older individuals.

Neurofilament Metabolism

The process involving the turnover and function of neurofilaments, protein structures essential for the maintenance and function of neurons.

Muscular Rigidity

A condition where muscles remain constantly contracted, causing stiffness or inflexibility of the affected muscles.